Through an extensive literature review and interviews with more than 50 experts, the Center project team identified 15 example technologies and grouped them into 5 broad categories that are significantly relevant to public health preparedness and response:
- Disease Detection, Surveillance, and Situational Awareness: Ubiquitous Genomic Sequencing and Sensing, Drone Networks for Environmental Detection, Remote Sensing for Agricultural Pathogens
- Infectious Disease Diagnostics: Microfluidic Devices, Handheld Mass Spectrometry, Cell-Free Diagnostics
- Distributed Medical Countermeasure Manufacturing: 3D Printing of Chemicals and Biologics, Synthetic Biology for Manufacturing MCMs
- Medical Countermeasure Distribution, Dispensing, and Administration:Microarray Patches for Vaccine Administration, Self-Spreading Vaccines, Ingestible Bacteria for Vaccination, Self-Amplifying mRNA Vaccines, Drone Delivery to Remote Locations
- Medical Care and Surge Capacity: Robotics and Telehealth, Portable Easy-to-Use Ventilator
The project team noted their list is not exhaustive or an endorsement of specific companies. The team used a modified version of DARPA’s Heilmeier Catechism to standardize the process of evaluating each technology and formulating guidance for funding decisions. That process informed the team’s high-level assessment of the readiness of each technology (from early development to being field-ready), the potential impact of the technology on GCBR reduction (from low to high), and the amount of financial investment that would be needed to meaningfully deploy the technology (from low to high). Details on these findings are included in the report.